P C Chem

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Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C₃N₂ ring but feature varied substituents. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedativemidazolam.

It is used in a number of manufacturing processes as a high value specialty chemical including the electronics industry, flavors and fragrances industry, specialty solvents, polymer crosslinking, and pharmaceutical industry. In 2004, annual global production of malonic acid and related diesters was over 20,000 metric tons. Potential growth of these markets could result from advances in industrial biotechnology that seeks to displace petroleum-based chemicals in industrial applications.

Malonic acid was listed as one of the top 30 chemicals to be produced from biomass by the US Department of Energy.

In food and drug applications, malonic acid can be used to control acidity, either as an excipient in pharmaceutical formulation or natural preservative additive for foods.^{[citation needed]}

Malonic acid is used as a building block chemical to produce numerous valuable compounds, including the flavor and fragrance compounds gamma-nonalactone, cinnamic acid, and the pharmaceutical compound valproate.

Malonic acid (up to 37.5% w/w) has been used to cross-link corn and potato starches to produce a biodegradable thermoplastic; the process is performed in water using non-toxic catalysts. Starch-based polymers comprised 38% of the global biodegradable polymers market in 2014 with food packaging, foam packaging, and compost bags as the largest end-use segments.

Eastman Kodak company and others use malonic acid and derivatives as a surgical adhesive.

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Resorcinol is also used as a chemical intermediate for the synthesis of pharmaceuticals and other organic compounds. It is used in the production of diazo dyes and plasticizers and as a UV absorber in resins.

An emerging use of resorcinol is as a template molecule in supramolecular chemistry. The -OH groups on resorcinol form hydrogen bonds to target molecules, holding them in the proper orientation for a reaction. Many such reactions are able to be carried out in the solid state, thereby reducing or eliminating the use of solvents that may be harmful to the environment. (see Green chemistry)

Resorcinol is an analytical reagent for the qualitative determination of ketoses (Seliwanoff's test).

Resorcinol is the starting material for resorcinarene molecules and the initiating explosive lead styphnate.

Resorcinol reacts with formaldehyde to form a thermoset resin which can form the basis of an aerogel.

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n cereals, ferulic acid is localized in the bran the hard outer layer of grain. In wheat, phenolic compounds are mainly found in the form of insoluble bound ferulic acid and be relevant to resistance to wheat fungal diseases. The highest known concentration of ferulic acid glucoside has been found in flax seed (4.1 +- 0.2 g/kg). It is also found in barley grain.

Asterid Eudicot plants can also produce ferulic acid. The tea brewed from the leaves of yacon (Smallanthus sonchifolius), a plant traditionally grown in the Northern and Central Andes, contains quantities of ferulic acid. In legumes, the white bean variety navy bean is the richest source of ferulic acid among the common bean (Phaseolus vulgaris) varieties. It is also found in horse grams (Macrotyloma uniflorum)

Although there are many sources of ferulic acid in nature, its bioavailability is limited based on the form in which it is present, with free ferulic acid having a poor water solubility hence poor bioavailability. In wheat grain, ferulic acid is found bound to cell wall polysaccharides, which has an effect on its release and absorption in the small intestine.

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t can be formed by fusing extract of aloes with potash.

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It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basichealth system.

USES:hlorhexidine is used in disinfectants (disinfection of the skin and hands), cosmetics (additive to creams, toothpaste, deodorants, and antiperspirants), and pharmaceutical products (preservative in eye drops, active substance in wound dressings and antiseptic mouthwashes). In endodontics chlorhexidine is used for root canal irrigation and as an intracanal dressing.

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We are engaged in offering 5-Chloro-2-Hydroxyacetophenone which finds application in varied industrial applications. Our valuable clients avail this chemical compound in large quantities, which is packed in properly labeled containers. The composition of this compound is balanced and is stable in different climatic conditions.

Product Categories Aromatic Acetophenones & Derivatives (substituted); Phenols and thiophenols; Aldehydes, Acetals & Ketones; Chlorine Compounds; Phenols; C7 to C8; Carbonyl Compounds; Ketones

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Pd(0)-catalyzed cross coupling reaction of 4′-iodoacetophenone with siloxane has been reported. Heck-Mizoroki reactions of 4′-iodoacetophenone with styrene catalyzed by Pd nanoparticles in the flow reactor has been reported.

We offer a range of 4-Methyl Phenacyl Bromide that is immensely used in the pharmaceutical and other allied industries. Our company provides it at the market leading prices for the clients. These are provided to our clients after they are passed through various stringent quality tests based on crucial parameters. We develop these as per the international industrial standards and are highly acknowledged for their purity and composition all across the Indian as well as overseas market.

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Osmium(VIII) oxide is also used in catalytic amounts in the Sharpless oxyamination to give vicinal amino-alcohols.

In combination with sodium periodate, OsO₄ is used for the oxidative cleavage of alkenes (Lemieux-Johnson oxidation) when the periodate serves both to cleave the diol formed by dihydroxylation, and to reoxidize the OsO₃ back to OsO₄. The net transformation is identical to that produced by ozonolysis. Below an example from the total synthesis of Isosteviol.

SAFTYOsO₄ is highly poisonous, even at low exposure levels, and must be handled with appropriate precautions. In particular, inhalation at concentrations well below those at which a smell can be perceived can lead to pulmonary edema and subsequent death. Noticeable symptoms can take hours to appear after exposure.

OsO₄ also stains the human cornea, which can lead to blindness if proper safety precautions are not observed. The permissible exposure limit for osmium(VIII) oxide (8 hour time-weighted average) is 200 g/m³.^[7] Osmium(VIII) oxide can penetrate plastics and therefore is stored in glass under refrigeration.^[14]

On April 6, 2004 British intelligence sources believed they had foiled a plot to detonate a bomb involving OsO₄.^[23] Experts interviewed by New Scientist affirmed osmium(VIII) oxide's toxicity, though some highlighted the difficulties of using it in a weapon osmium(VIII) oxide is very expensive. The osmium(VIII) oxide may be destroyed by the blast; remaining toxic fumes may also be dispersed by the blast.

In normal individuals, a 25 g oral dose of D-xylose will be absorbed and excreted in the urine at approximately 4.5 g in 5 hours. A decreased urinary excretion of D-xylose is seen in conditions involving the GI mucosa, such as small intestinal bacterial overgrowth and Whipple's disease. In cases of bacterial overgrowth, the values of D-Xylose absorption return to normal after treatment with antibiotics. In contrast, if the D-xylose urinary excretion is not normal after a course of antibiotics, then the problem must be due to a non-infectious cause of malabsorption (i.e., celiac disease).